EXPERIMENTAL PHARMACOLOGY – 2 (Bridges the Gap Between Animal Models and Computer Simulation Models)

1 Introduction to in-vitro pharmacology and physiological salt solutions | 2. Effect of drugs on isolated frog heart | 3. Effect of drugs on blood pressure and heart rate of dog | 4. Study of diuretic activity of drugs using rats / mice | 5. DRC of acetylcholine using frog rectus abdominis muscle | 6. Effect of physostigmine and atropine on DRC of acetylcholine using frog rectus abdominis muscle and rat ileum respectively |   7. Bioassay of histamine using guinea pig ileum by matching method | 8. Bioassay of oxytocin using rat uterine horn by interpolation method | 9. Bioassay of serotonin using rat fundusstrip by three point bioassay | 10. Bioassay of acetylcholine using rat ileum / colon by four point bioassay | 11. Determination of PA₂value of prazosin using rat anococcygeus muscle (by Schilds plot method). | 12. Determination of PD₂ value using guinea pig ileum | 13. Effect of spasmogens and spasmolytics using rabbit jejunum | 14. Anti-inflammatory activity of drugs using carrageenan induced paw-edema model | 15. Analgesic activity of drug using central and peripheral methods.